How Pathogens Hijack Host Plants

How viruses hijack the ERAD tuning machinery.

An essential step during the intracellular life cycle of many positive-strand RNA viruses is the rearrangement of host cell membranes to generate membrane-bound replication platforms. For example, Nidovirales and Flaviviridae subvert the membrane of the endoplasmic reticulum (ER) for their replication. However, the absence of conventional ER and secretory pathway markers in virus-induced ER-der...

Phagosome-lysosome Fusion Hijack - An Art of Intracellular Pathogens

Phagosome-lysosome Fusion Hijack An Art of Intracellular Pathogens RAMESHWARAM NAGENDER RAO1,#, ROHINI SHRIVASTAVA1,2,#, GOURANGO PRADHAN1,2,#, PARUL SINGH1,2 and SANGITA MUKHOPADHYAY1,* 1Sangita Mukhopadhyay, Laboratory of Molecular Cell Biology, Centre for DNA Fingerprinting and Diagnostics (CDFD), Laboratory Block: Tuljaguda (Opp. MJ Market), Nampally, Hyderabad 500 001, India 2Graduate Stud...

How does Agrobacterium virulence protein VirE2 hijack host actomyosin motility system?

ARTICLE HISTORY Received 3 December 2017 Accepted 6 December 2017 ABSTRACT Agrobacterium tumefaciens has the ability to transform a wide range of eukaryotes by transferring single-stranded (ss) DNA (T-DNA) into the host cells. During the process, the bacterium also delivers abundant amount of ssDNA binding protein VirE2 into the host cytoplasm, where multiple VirE2 molecules bind and coat the T...

Trypanosome pathogens of plants

Hijack it, change it: how do plant viruses utilize the host secretory pathway for efficient viral replication and spread?

The secretory pathway of eukaryotic cells has an elaborated set of endomembrane compartments involved in the synthesis, modification, and sorting of proteins and lipids. The secretory pathway in plant cells shares many features with that in other eukaryotic cells but also has distinct characteristics important for fundamental cell and developmental processes and for proper immune responses. Rec...